Breasts is heterogeneously dense

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Women whose breasts appear dense on mammograms have a higher risk for some aggressive breast cancers. One of the strongest known risk factors for breast cancer is high breast density — that is, relatively little fat in the breast and more connective and glandular tissue, as seen on a mammogram. Now, a study has found that higher breast density in postmenopausal women increases the risk of specific types of breast cancer, including some that have a relatively poorer prognosis.

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Breast density is one of the strongest predictors of the failure of mammography to detect cancer. Up to half of breast cancers cannot be seen on the mammogram in women with dense breasts. This leads to missed cancers that are discovered at later stages, resulting in more invasive treatments and a poorer prognosis.

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To better direct supplemental imaging discussions, we determined which combinations of breast cancer risk and Breast Imaging Reporting and Data System BI-RADS breast density categories were associated with high interval cancer rates. Five-year risk was low-average Breast density should not be the sole criterion for deciding whether supplemental imaging is justified because not all women with dense breasts have high interval cancer rates.

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About half the women who get mammograms have dense breasts, meaning their breasts have an increased amount of glandular tissue that may develop into cancer. Since dense breast tissue and lumps—both benign and cancerous—appear white on a mammogramthe tests may not distinguish between normal and abnormal tissue and may be less accurate for women with dense breasts. Experts say such women should be informed about their condition so they can take the steps necessary to protect their future health.

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The breast contains ducts, glands, fibrous connective tissue, and fatty tissue. Breasts that are dense or very dense have a lot of fibrous, connective tissue and less fatty tissue. Breasts that are not dense contain almost all fatty tissue and very little fibrous tissue.

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Breasts contain glandular, connective, and fat tissue. Breast density is a term that describes the relative amount of these different types of breast tissue as seen on a mammogram. Dense breasts have relatively high amounts of glandular tissue and fibrous connective tissue and relatively low amounts of fatty breast tissue.

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Some mammogram reports sent to women mention breast density. Your health care provider can also tell you if your mammogram shows that you have dense breasts. In some states, women whose mammograms show heterogenously dense or extremely dense breasts must be told that they have dense breasts in the summary of the mammogram report that is sent to patients sometimes called the lay summary.

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Breasts that are dense have more gland tissue that makes and drains milk and supportive tissue also called stroma that surrounds the gland. Having dense breasts has been linked to a much higher risk of breast cancer. At the same time, having dense breasts also can make it harder for mammograms to detect breast cancer. Twenty-one states have laws requiring women be notified if they have dense breasts and that the women be advised to talk to their doctor about additional screening tests.

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The idea was originally met with scepticism, but consensus now is that it is indeed a true risk element and of interest to screening mammography. Essentially, breast density is a comparison of the relative amounts of fat versus fibroglandular tissues in the breast. Fibroglandular parenchyma, basically means breast tissue.

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Breast density is a proportional measure of the glandular, connective and fatty tissues within a woman's breasts. It is most commonly determined using mammography, a diagnostic test that uses low dose x-rays. Having dense breasts is not an abnormal condition; in fact, about half of all women over 40 have dense breasts.

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